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The major UK trial will study Aspirin as a treatment with Covid-19



Conventional aspirin inside the vial.

Conventional aspirin inside the vial.
Photo: Tim Boyle (beautiful images)

120 years-a drug that is about to be tested as a possible treatment for covid-19 disease. This week, researchers from the UK announced They will begin to include aspirin as one of the continuously researched treatments The RECOVERY trial – one of the largest and most influential clinical trials conducted during a pandemic. They hope good aspirin-know againstCoagulation properties can prevent severe patients from dying.

Trials RECOVERED so far more than 16,000 patients have been hospitalized with covid-19 in the UK. These patients were randomly selected for standard care alone or for multiple treatments tested in addition to standard care. RECOVERY is the first major trial to find evidence that conventional steroids can be a lifesaver for serious cases; The trial also showed little or no evidence that other treatments, including the anti-malarial hydroxychloroquine, did a lot. That is detect available shaping a lot current treatment criteria for patients with covid-19.

RECOVERY has continued to experiment Another promising option for covid-19, the most recent is aspirin. An estimated 2,000 patients are expected to receive one dose of aspirin, along with standard care, and they will be compared with those who do not receive additional care. People with an aspirin allergy or recent severe bleeding will be excluded from the test. The main result to be studied will be the death rate of people after 28 days.

Many serious complications of covid-19 are thought to be related blood-cthe problem of hitting the subject. Some researchers have Discuss, and at least one recent study did suggestions, that the use of aspirin may lead to a greater survival in covid-19 patients. But it usually takes data from large-scale randomized and controlled clinical trials for clinicians to widely apply new therapies to their arsenal – data RECOVERY hopes to deliver.

“Aspirin is widely used to prevent blood clots in many other conditions, including heart attacks,” said Martin Landray, a researcher at Oxford University and one of the main scientists on the project. , stroke and preeclampsia in pregnant women. notification of the new branch of the Friday trial. “But enrolling patients in a randomized trial like RESTORE is the only way to assess whether there are clear benefits for covid-19 patients and whether those benefits outweigh any effects. are there any potential side effects such as bleeding risk? ”

Current treatments, such as steroids, It only offers modest life-saving benefits in the most severe cases and there is no clear treatment that proves effective in preventing it. word case worsens. So any help that aspirin can provide is essential, especially when pandemic has gotten worse all over the world. Just this week has seen record numbers of cases in places like the United States, while the resurgence of the disease across Europe has contributed to new courses and some of the deadliest days of this entire epidemic in the world.

That said, it will probably take months before results above aspirin will appear from RESTORE. Other treatments are currently being tested in The trial included the antibiotic azithromycin, the anti-inflammatory tocilizumab, and an experimental antibody cocktail in the lab developed by the Regeneron company.


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