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T cells respond to Covid-19 six months after infection, the study found



A medical professional applies a nasal swab during a test at the Covid-19 Orange County Health Service driving site at Barnett Park in Orlando, Fla., Thursday, October 29, 2020.

Joe Burbank | Tribune news service | beautiful images

A new study suggests that cellular immunity, or “T cells”

;, against Covid-19 may appear within six months of primary infection.

Research by the UK Coronavirus Immunology Association (UK-CIC), British Public Health and the Manchester University NHS Foundation Trust found a “strong T-cell response” to the six-month coronavirus. after infection.

T cells that are part of our immune system attack cells that have been infected with a virus or other pathogen and they help the cells to produce other antibodies in the immune system. Scientists studied the response of T-cells to the coronavirus to see the long-term degree of any immune response in already acquired and recovered individuals from Covid-19.

This latest study looked at 100 individuals who tested positive for coronavirus in March and April 2020 but did not hospitalize for the virus. All 100 people experienced mild or moderate symptoms or no symptoms (56 vs. 44 people), the study noted.

Serum samples are collected monthly to measure antibody levels, and blood samples are taken after six months to assess the response of cells (T cells) to the virus.

A series of analyzes have been performed to evaluate various aspects of T cell response including the degree of response and response to different proteins from the virus, the study noted.

“T-cell responses have been present in all individuals six months after SARS-CoV-2 infection, suggesting that“ a strong cell memory against the virus persists, ”it said. at least six months ”.

However, the study found that “the response size of T cells varies from person to person, significantly higher (50%) in those who had experienced symptomatic disease at the time of infection six months earlier. . ” The research has yet to be published or reviewed.

The Covid-19 puzzle piece

The finding can enhance our understanding of how immunity works against coronavirus, as well as provide information on future vaccine strategies, research led by Dr. Shamez Ladhani, Epidemiological consultant at British Public Health – author – note.

“Cell immunity is a very important but complex part of the Covid-19 puzzle and it is important to do more research in this area. However, initial results show the response of the cell. T cells may outlive the initial antibody response, which could have a significant effect on Covid vaccine development and immunological research. ”

The study notes that more research is now needed to assess whether this immune response is sustained or not and to better understand the strength of the cellular immune response relative to regeneration. infection like.

Professor Paul Moss, head of the UK Coronavirus Society of Immunology from the University of Birmingham, says more research is needed to find out if people with Covid-19 symptoms are safer from reinfection. in the future or not.

“Interestingly, we have found that at this time, cellular immunity is stronger in symptomatic people than in asymptomatic ones. We are currently in need of more research to Find out if people with symptoms are better protected against future reinfection. “


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