FC Dallas will face Nashville SC at 7:30 pm in the opening match of two head-to-head matches.
Both teams were forced to withdraw from the recent MLS is Back tournament due to a Covid-19 outbreak among staff and players.
MLS is the first major team sports tournament to host a match against fans since the coronavirus pandemic forced tournaments to suspend or postpone their respective seasons in March.
NBA, NHL and MLB have returned or started their season, but no fans attended.
The team says not accepting cash at franchise counters to minimize physical interactions. No paper tickets are being distributed, as all tickets will be distributed and processed through the AXS ticketing app.
Texas has now recorded at least 518,150 confirmed coronavirus infections – the third most among US states – and more than 9,255 deaths, according to a Johns Hopkins University tally.