- A study on coronavirus immunity confirms recent research that the common cold can simply form an immune defense system that remains active against COVID-19 and it has nothing to do with it. to neutralizing antibodies that appear after infection.
- The immune system produces T cells that can remember pathogens, like other coronaviruses in humans that cause frequent colds. Those T cells have been found to provide some protection from COVID-19.
- The findings are promising and explain exactly how the immune response works when dealing with any pathogen, including SARS-CoV-2, said Dr. Anthony Fauci.
A few days ago, a study found that pre-infection with one of the coronaviruses in someone else caused the common cold may make some people immune to COVID-19. The initial infection that causes frequent colds produces T cells, which can then recognize new coronavirus and accelerate the immune response against COVID-19. This may explain why some people develop small versions of COVID-19, while others experience severe symptoms. This study is in line with other studies released this year and may be helpful in studying COVID-19 immunity in the years to come, especially when a vaccine arrives.
Previously, a study showed that the neutralizing antibodies produced after a SARS-CoV-2 infection disappear from the immune system, causing some people to worry that reinfection might be possible for a while. short. But researchers have explained the immune system’s dual defense mechanisms that include the creation of both antibodies and T cells that can memorize pathogens. Some vaccine candidates have reached the final stages of clinical trials that induce both antibody neutralization and T-cell responses in volunteers, which is a promising development step for immunity. long term translation.
Dr. Anthony Fauci mentioned new research that explains how the common cold can induce COVID-19 immunity, explaining coronavirus immunity in the way that it should be done in the first place.
Fauci says of the new study that it may explain why some people have no symptoms of COVID-19 after being infected, while others need hospitalization and are at risk of death.
“One of the things I don’t think has been greatly emphasized in trying to deal with, scientifically, COVID-19 outbreaks, as well as vaccine development and testing, is that we have focus entirely on antibodies. experiment, ”said Fauci McClatchy on immunological research. “There is another equally important component of the immune system.”
Published in Science, research funded by the National Institute of Allergy and Infectious Diseases (NIAID), which Fauci has led for more than three decades.
“If you look at it metaphorically as an army with different levels of defense, then the antibodies prevent the virus from entering,” Fauci explained. So that’s like the first line of defense ”. “For the viruses that escape and infect some cells, the T cells go in and kill the infected cells or stop them.”
A virologist at Columbia University used a military-like approach to differentiate neutral antibodies from T cells that could destroy the infected cells and begin to produce more antibodies. “None of our soldiers had been trained before,” said Rasmussen. “But the T-cell discovery suggests that perhaps the cavalry was indeed prepared for this virus. Perhaps they already know a bit about how to combat it. And perhaps that is helping the overall military to stop the virus from entering.
“Scientifically, that’s good news, because otherwise we’re completely naive about this virus and it’s brand new,” she said. “If there is anything that can give us an edge against it, even in our bodies and our immune systems, then for me that is great news and very promising. . “
Fauci warns that T cells don’t live forever, and this may explain why some patients have a slow immune response to infection. “It’s like a one or two punch,” said Fauci. “Imagine the T cells that you created to react a few years ago – three, four, five years ago – when you were exposed to a relatively benign coronavirus that caused the common cold. , it can actually exist, and when you’ve been exposed to SARS-Coronavirus-2, there may be some degree of protection. “
Someone who hasn’t been exposed to a common coronavirus for decades may not have the same T-cell memory as someone who has a common cold.
Bill Gates also commented on the matter over the weekend, saying CNN that exposure to other coronaviruses could explain differences between different regions of the world. “Within a few months, we will really understand this,” Gates said, adding that the popularity of bats carrying coronaviruses in Asia may have boosted cellular immunity. T of the population. “They could have had this cross-protection which meant the spread of the epidemic was not strong there.”
More research is needed to determine exactly how these T cells work in COVID-19 and how they affect the prognosis of infection.