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Here are the coronavirus stories that Medscape editors globally think you need to know about today.
New research indicates that an N95 respirator that is out of date or has been used and remanufactured may be an accepted alternative to the standard new N95 disposable respirator.
The researchers tested the fitted filtration efficiency (FFE) of 29 different suitably matched mask alternatives worn by a male and female volunteer performing a series of repetitive movements of body, head and facial muscles to reproduce typical occupational activities.
The respirators they tested included N95 respirators that are 11 years out of date, N95 respirators that have been disinfected with ethylene oxide and hydrogen peroxide or steam, surgical masks and gas masks that have not yet been used. National Institute of Occupational Safety and Health (approved by NIOSH)).
The co-authors of a linked editorial write that although the apparent “imperfect” FFE of laboratory and surgical masks are not NIOSH approved, “there are reasons for optimism about efficacy. results in their real world. “
Chloroquine has been associated with serious psychiatric side effects
Taking chloroquine could be associated with serious psychiatric side effects, even in unmarried patients or a personal history of psychosis, the researchers suggest. The review refers to a study of the FDA’s Adverse Event Reporting System database, a clinical trial for malaria prophylaxis, and reports and case series.
“As a rheumatologist using hydroxychloroquine at a dose of 400 mg / day, I don’t think we need to worry about a serious problem. [psychiatric] side effects, “Nilanjana Bose, MD, who was not involved in the review, said Medscape medical news.
“These are the most likely side effects associated with psychiatrists,” another expert said.
COVID-19 cases in US children skyrocketed in late July
A new report by the American Academy of Pediatrics and the Children’s Hospital Association shows that nearly 339,000 children have tested positive for COVID-19 since the outbreak in the US. Cases are up 40% in the second half of July compared to the previously reported total. There are 97,078 new cases.
According to the report, most of the new infections occurred in states in the South and the West, based on data from 49 states, New York City, District of Columbia, Puerto Rico and Guam.
Most residents asked if their training would prepare them for COVID-19 in a Medscape survey said they were not yet or they were unsure.
While 40% say they feel prepared, 30% say they don’t feel prepared and 31% say they are not sure. Data included responses from 1659 US medical residents.
Kidney and COVID-19
The incidence of acute kidney injury in hospitalized COVID-19 patients has fluctuated widely in reports of different cohort groups, which “indicates that we do not fully understand the process and that they are not. We don’t know what’s going on or the obvious risk, “New York City’s Mount Sinai Hospital transplant nephrologist Samira Farouk said in a video commentary by Medscape.
She and Duke University nephrologist Matthew Sparks discussed what is known and what remains a mystery, about how COVID-19 affects a patient’s kidneys. Farouk says whether SARS-CoV-2 can directly infect and cause kidney damage is “a multi-million dollar question.” “There is convincing evidence for both sides.”
As frontline health care workers caring for patients with COVID-19, they are committed to the hard work, fatigue and also at risk of infection. Thousands of people all over the world have died.
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Ellie Kincaid is the managing editor of Medscape. Previously she wrote about healthcare for Forbes, Wall Street Journal and Nature Medicine. Her can be reached at firstname.lastname@example.org or on Twitter @ellie_kincaid.
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