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An immunity to Coronavirus persists for at least six months, research results



The blood sample is about to be tested for covid-1<div class="e3lan e3lan-in-post1"></div>9 antibodies at a Moscow clinic on May 15, 2020

The blood sample is about to be tested for covid-19 antibodies at a Moscow clinic on May 15, 2020
Photo: Vasily Maximov (beautiful images)

This week’s new study offers some hope for at least one aspect of our immunity to the covid-19-induced coronavirus. Research, conducted by researchers in the UK, has found evidence that some T cells produced to fight coronavirus during infection continue to show a “strong” response at least six. month later. This cellular immune response is thought to play a key role in preventing reinfection or reducing the severity of the subsequent infection, along with other components of our immunity like resistance. can.

New research is the job of Coronavirus UK Society of Immunology, a national study supported by the UK government and involving several universities. As part of the project, the researchers followed 100 volunteers who all tested positive for coronavirus antibodies in March or April. Although some people developed symptoms at the time. Diagnostic score but no one needed hospitalization.

T cells are one of the main cells of the immune system. They perform a variety of tasks during infection, from directly trying to kill infected cells to helping other cells do their jobs better, including reproductive cells. proteins that we call antibodies. Like antibodies, our bodies can make special T cells that “remember” the pathogen in the past and can act when it tries to re-infect us. However, compared to studying how antibodies react to bacteria, a person’s cellular immune response is more complex and difficult to measure. That makes this one of the largest and most important of its kind.

Initial result, release in an article on the pre-printed bioRxiv website on Tuesday, which certainly looks very encouraging. The researchers found that all the volunteers developed the virus-specific T cells as soon as they were diagnosed. And when the volunteers’ blood was studied six months later, these T cells seemed to still be in their system.

“To our knowledge, our study is the first in the world to show that strong cellular immunity persists six months after infection in people experiencing mild / average or asymptomatic, ”said Paul Moss, a hematologist at Birmingham University and one of the project’s key scientists, in one declare released by the Third Consortium.

Immunity to diseases like covid-19, as we have discuss before, it was a complicated mess. Some studies have suggested that coronavirus-specific antibodies may fade away within as little as three months, but other studies have suggested that the most important antibodies – those that directly suppress microbes -Remove the infection to new cells – Can remain in most people who survive for at least five months. And still other parts of the immune system are involved in covid-19 has not been studied in much detail, like cell B

Experts hope our natural immunity to coronavirus will eventually begin to weaken, simply based on our history with other coronaviruses that make us sick (how it works of vaccine-induced immunity is still uncertain). But findings from this new study and others suggest that some level of protection should last for more than a few months. This protection may not necessarily prevent reinfection in all cases (really, we’re starting to see a litter of reinfection cases now. report worldwide), but it will likely reduce the impact of a second infection if it does occur, experts told Gizmodo.

Much remains to be done about our immune response to covid-19, and the findings from this study will provide new pathways for follow-up scientists.

For example, research shows that people who feel sick tend to have a stronger T-cell response than people without symptoms, which may suggest that symptom survivors are better protected. The level of human T-cell response over time is also strongly correlated with their antibody levels to the virus, while greater onset of T-cell response is associated with impairment. decrease in antibodies more slowly. That means any future vaccine will have to induce a strong T-cell response in addition to an antibody response to be as effective as possible.


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